AmOnco15TM cancer gene panel targets the most relevant regions in 15 cancer associated genes. The gene content is most commonly cited by organizations such as National Comprehensive Cancer Network (NCCN), European Society for Medical Oncology (EMSO) and industry thought leaders. The analysis includes single nucleotide variants (SNVs) and insertions and deletions (indels).

List of Genes covered in AmOnco15™

AKT1 ERBB2 GNAQ MET PIK3CA
BRAF FOXL2 KIT NRAS RET
EGFR GNA11 KRAS PDGFRA TP53

AmOnco15™ Specifications

Regions Analyzed Hot spot regions of 15 cancer genes
Sequencing method PCR Amplification followed Illumina Next Generation Sequencing; 250 amplicons in 44 kb region
Sequencing depth >500X
Assay Sensitivity and Specificity >99%
Sample requirement FFPE tumor tissues; 20 ng of DNA
Sample type FFPE tumor tissues
Turn-around time 1 week
Variant frequency >5%